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Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units

Long non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated by their structures. However, our structural knowledge for most lncRNAS is limited to sequence-base...

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Detalles Bibliográficos
Autores principales: Chorostecki, Uciel, Saus, Ester, Gabaldón, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192489/
https://www.ncbi.nlm.nih.gov/pubmed/34141143
http://dx.doi.org/10.1016/j.csbj.2021.05.045