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TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate immune cells encounter different mechanical cues in both health and disease to adapt their behaviors. However, the impact of mechanical sensing signals on TLR4 signal-mediated innate immune response remains u...

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Detalles Bibliográficos
Autores principales: Geng, Jing, Shi, Yiran, Zhang, Jinjia, Yang, Bingying, Wang, Ping, Yuan, Weihong, Zhao, Hao, Li, Junhong, Qin, Funiu, Hong, Lixin, Xie, Changchuan, Deng, Xianming, Sun, Yujie, Wu, Congying, Chen, Lanfen, Zhou, Dawang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192512/
https://www.ncbi.nlm.nih.gov/pubmed/34112781
http://dx.doi.org/10.1038/s41467-021-23683-y