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TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate immune cells encounter different mechanical cues in both health and disease to adapt their behaviors. However, the impact of mechanical sensing signals on TLR4 signal-mediated innate immune response remains u...
Autores principales: | Geng, Jing, Shi, Yiran, Zhang, Jinjia, Yang, Bingying, Wang, Ping, Yuan, Weihong, Zhao, Hao, Li, Junhong, Qin, Funiu, Hong, Lixin, Xie, Changchuan, Deng, Xianming, Sun, Yujie, Wu, Congying, Chen, Lanfen, Zhou, Dawang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192512/ https://www.ncbi.nlm.nih.gov/pubmed/34112781 http://dx.doi.org/10.1038/s41467-021-23683-y |
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