CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice

CD38 is the main enzyme for nicotinamide adenine dinucleotide (NAD) degradation in mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and aging-related diseases. Our study showed that CD38 deficiency significantly alleviated angiotensin II (Ang II)-induced vascular remo...

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Detalles Bibliográficos
Autores principales: Gan, Lu, Liu, Demin, Liu, Jing, Chen, Erya, Chen, Chan, Liu, Lian, Hu, Hang, Guan, Xiaohui, Ma, Wen, Zhang, Yanzi, He, Yarong, Liu, Bofu, Tang, Songling, Jiang, Wei, Xue, Jianxin, Xin, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192533/
https://www.ncbi.nlm.nih.gov/pubmed/34112762
http://dx.doi.org/10.1038/s41392-021-00625-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192533/
https://www.ncbi.nlm.nih.gov/pubmed/34112762
http://dx.doi.org/10.1038/s41392-021-00625-0

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