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Protocol for crystal structure determination of the antagonist-bound human cannabinoid receptor CB2

Human cannabinoid receptor CB2 plays an important role in the immune system and is an attractive therapeutic target for pain and for inflammatory and neurodegenerative diseases. However, the structural basis of CB2 agonist selectivity is still elusive. Here, we describe a detailed protocol for the d...

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Detalles Bibliográficos
Autores principales: Shen, Ling, Li, Xiaoting, Liu, Junlin, Liu, Kaiwen, Liu, Zhi-Jie, Hua, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192724/
https://www.ncbi.nlm.nih.gov/pubmed/34151302
http://dx.doi.org/10.1016/j.xpro.2021.100584