Ventral tegmental area GABA neurons mediate stress-induced blunted reward-seeking in mice

Decreased pleasure-seeking (anhedonia) forms a core symptom of depression. Stressful experiences precipitate depression and disrupt reward-seeking, but it remains unclear how stress causes anhedonia. We recorded simultaneous neural activity across limbic brain areas as mice underwent stress and disc...

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Detalles Bibliográficos
Autores principales: Lowes, Daniel C., Chamberlin, Linda A., Kretsge, Lisa N., Holt, Emma S., Abbas, Atheir I., Park, Alan J., Yusufova, Lyubov, Bretton, Zachary H., Firdous, Ayesha, Enikolopov, Armen G., Gordon, Joshua A., Harris, Alexander Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192742/
https://www.ncbi.nlm.nih.gov/pubmed/34112787
http://dx.doi.org/10.1038/s41467-021-23906-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192742/
https://www.ncbi.nlm.nih.gov/pubmed/34112787
http://dx.doi.org/10.1038/s41467-021-23906-2

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