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Ventral tegmental area GABA neurons mediate stress-induced blunted reward-seeking in mice
Decreased pleasure-seeking (anhedonia) forms a core symptom of depression. Stressful experiences precipitate depression and disrupt reward-seeking, but it remains unclear how stress causes anhedonia. We recorded simultaneous neural activity across limbic brain areas as mice underwent stress and disc...
Autores principales: | Lowes, Daniel C., Chamberlin, Linda A., Kretsge, Lisa N., Holt, Emma S., Abbas, Atheir I., Park, Alan J., Yusufova, Lyubov, Bretton, Zachary H., Firdous, Ayesha, Enikolopov, Armen G., Gordon, Joshua A., Harris, Alexander Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192742/ https://www.ncbi.nlm.nih.gov/pubmed/34112787 http://dx.doi.org/10.1038/s41467-021-23906-2 |
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