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Mechanistic insights into TNFR1/MADD death domains in Alzheimer’s disease through conformational molecular dynamic analysis

Proteins are tiny players involved in the activation and deactivation of multiple signaling cascades through interactions in cells. The TNFR1 and MADD interact with each other and mediate downstream protein signaling pathways which cause neuronal cell death and Alzheimer’s disease. In the current st...

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Detalles Bibliográficos
Autores principales: Hassan, Mubashir, Zahid, Sara, Alashwal, Hany, Kloczkowski, Andrzej, Moustafa, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192743/
https://www.ncbi.nlm.nih.gov/pubmed/34112868
http://dx.doi.org/10.1038/s41598-021-91606-4