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A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis

Camptothecin and its derivatives are widely used for treating malignant tumors. Previous studies revealed only a limited number of candidate genes for camptothecin biosynthesis in Camptotheca acuminata, and it is still poorly understood how its biosynthesis of camptothecin has evolved. Here, we repo...

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Detalles Bibliográficos
Autores principales: Kang, Minghui, Fu, Rao, Zhang, Pingyu, Lou, Shangling, Yang, Xuchen, Chen, Yang, Ma, Tao, Zhang, Yang, Xi, Zhenxiang, Liu, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192753/
https://www.ncbi.nlm.nih.gov/pubmed/34112794
http://dx.doi.org/10.1038/s41467-021-23872-9