Cargando…

DNCON2_Inter: predicting interchain contacts for homodimeric and homomultimeric protein complexes using multiple sequence alignments of monomers and deep learning

Deep learning methods that achieved great success in predicting intrachain residue-residue contacts have been applied to predict interchain contacts between proteins. However, these methods require multiple sequence alignments (MSAs) of a pair of interacting proteins (dimers) as input, which are oft...

Descripción completa

Detalles Bibliográficos
Autores principales: Quadir, Farhan, Roy, Raj S., Halfmann, Randal, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192766/
https://www.ncbi.nlm.nih.gov/pubmed/34112907
http://dx.doi.org/10.1038/s41598-021-91827-7