Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine

Fluorogenic RNA aptamers are synthetic functional RNAs that specifically bind and activate conditional fluorophores. The Chili RNA aptamer mimics large Stokes shift fluorescent proteins and exhibits high affinity for 3,5-dimethoxy-4-hydroxybenzylidene imidazolone (DMHBI) derivatives to elicit green...

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Detalles Bibliográficos
Autores principales: Mieczkowski, Mateusz, Steinmetzger, Christian, Bessi, Irene, Lenz, Ann-Kathrin, Schmiedel, Alexander, Holzapfel, Marco, Lambert, Christoph, Pena, Vladimir, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192780/
https://www.ncbi.nlm.nih.gov/pubmed/34112799
http://dx.doi.org/10.1038/s41467-021-23932-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192780/
https://www.ncbi.nlm.nih.gov/pubmed/34112799
http://dx.doi.org/10.1038/s41467-021-23932-0

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