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Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy

Targeting tumor-associated macrophages (TAMs) is a promising strategy to modify the immunosuppressive tumor microenvironment and improve cancer immunotherapy. Monoamine oxidase A (MAO-A) is an enzyme best known for its function in the brain; small molecule MAO inhibitors (MAOIs) are clinically used...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Chen, Wang, Xi, Yu, Jiaji, Ma, Feiyang, Li, Zhe, Zhou, Yang, Zeng, Samuel, Ma, Xiaoya, Li, Yan-Ruide, Neal, Adam, Huang, Jie, To, Angela, Clarke, Nicole, Memarzadeh, Sanaz, Pellegrini, Matteo, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192781/
https://www.ncbi.nlm.nih.gov/pubmed/34112755
http://dx.doi.org/10.1038/s41467-021-23164-2