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Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes

Myeloma bone disease is a major complication in multiple myeloma affecting quality of life and survival. It is characterized by increased activity of osteoclasts, bone resorbing cells. Myeloma microenvironment promotes excessive osteoclastogenesis, a process of production of osteoclasts from their p...

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Detalles Bibliográficos
Autores principales: Byrgazov, Konstantin, Lind, Thomas, Rasmusson, Annica J., Andersson, Claes, Slipicevic, Ana, Lehmann, Fredrik, Gullbo, Joachim, Melhus, Håkan, Larsson, Rolf, Fryknäs, Mårten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192817/
https://www.ncbi.nlm.nih.gov/pubmed/34150958
http://dx.doi.org/10.1016/j.bonr.2021.101098