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Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes
Myeloma bone disease is a major complication in multiple myeloma affecting quality of life and survival. It is characterized by increased activity of osteoclasts, bone resorbing cells. Myeloma microenvironment promotes excessive osteoclastogenesis, a process of production of osteoclasts from their p...
Autores principales: | Byrgazov, Konstantin, Lind, Thomas, Rasmusson, Annica J., Andersson, Claes, Slipicevic, Ana, Lehmann, Fredrik, Gullbo, Joachim, Melhus, Håkan, Larsson, Rolf, Fryknäs, Mårten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192817/ https://www.ncbi.nlm.nih.gov/pubmed/34150958 http://dx.doi.org/10.1016/j.bonr.2021.101098 |
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