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C. elegans survival assays to discern global and transcription-coupled nucleotide excision repair

Global genome nucleotide excision repair (GG-NER) and transcription-coupled nucleotide excision repair (TC-NER) protect cells against a variety of helix-distorting DNA lesions. In C. elegans, GG-NER primarily acts in proliferative germ cells and embryos, while TC-NER acts in post-mitotic somatic cel...

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Detalles Bibliográficos
Autores principales: van der Woude, Melanie, Lans, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192855/
https://www.ncbi.nlm.nih.gov/pubmed/34151304
http://dx.doi.org/10.1016/j.xpro.2021.100586