Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

Insulin sensitizers and incretin mimetics are antidiabetic agents with vastly different mechanisms of action. Thiazolidinedione (TZD) insulin sensitizers are associated with weight gain, whereas glucagon-like peptide-1 receptor agonists can induce weight loss. We hypothesized that combination of a T...

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Detalles Bibliográficos
Autores principales: Kamm, Dakota R., Pyles, Kelly D., Sharpe, Martin C., Healy, Laura N., Colca, Jerry R., McCommis, Kyle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192871/
https://www.ncbi.nlm.nih.gov/pubmed/34022222
http://dx.doi.org/10.1016/j.jbc.2021.100807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192871/
https://www.ncbi.nlm.nih.gov/pubmed/34022222
http://dx.doi.org/10.1016/j.jbc.2021.100807

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