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The promiscuous binding pocket of SLC35A1 ensures redundant transport of CDP-ribitol to the Golgi

The glycoprotein α-dystroglycan helps to link the intracellular cytoskeleton to the extracellular matrix. A unique glycan structure attached to this protein is required for its interaction with extracellular matrix proteins such as laminin. Up to now, this is the only mammalian glycan known to conta...

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Detalles Bibliográficos
Autores principales: Ury, Benoît, Potelle, Sven, Caligiore, Francesco, Whorton, Matthew R., Bommer, Guido T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192872/
https://www.ncbi.nlm.nih.gov/pubmed/34015330
http://dx.doi.org/10.1016/j.jbc.2021.100789