Memantine shifts cancer cell metabolism via AMPK1/2 mediated energetic switch in A549 lung cancer cells

Memantine is used to prevent glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. As glutamine is one of the major source of anabolism in fast growing cancer cells, we aimed to interfere with the cancer cell metabolism in A549 lung cancer cells by using memantine. The...

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Detalles Bibliográficos
Autores principales: Albayrak, Gulsah, Demirtas Korkmaz, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192876/
https://www.ncbi.nlm.nih.gov/pubmed/34121969
http://dx.doi.org/10.17179/excli2020-2890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192876/
https://www.ncbi.nlm.nih.gov/pubmed/34121969
http://dx.doi.org/10.17179/excli2020-2890

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