Cargando…

Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation

Alzheimer's disease (AD) is a progressive mental disorder that brings a huge economic burden to the healthcare systems. During this illness, acetylcholine levels in the cholinergic systems gradually diminish, which results in severe memory loss and cognitive impairments. Moreover, Butyrylcholin...

Descripción completa

Detalles Bibliográficos
Autores principales: Nazari, Maryam, Rezaee, Elham, Hariri, Roshanak, Akbarzadeh, Tahmineh, Tabatabai, Sayyed Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192883/
https://www.ncbi.nlm.nih.gov/pubmed/34121977
http://dx.doi.org/10.17179/excli2021-3569