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Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation
Alzheimer's disease (AD) is a progressive mental disorder that brings a huge economic burden to the healthcare systems. During this illness, acetylcholine levels in the cholinergic systems gradually diminish, which results in severe memory loss and cognitive impairments. Moreover, Butyrylcholin...
Autores principales: | Nazari, Maryam, Rezaee, Elham, Hariri, Roshanak, Akbarzadeh, Tahmineh, Tabatabai, Sayyed Abbas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192883/ https://www.ncbi.nlm.nih.gov/pubmed/34121977 http://dx.doi.org/10.17179/excli2021-3569 |
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