Lentiviral vector induces high-quality memory T cells via dendritic cells transduction

We report a lentiviral vector harboring the human β2-microglobulin promoter, with predominant expression in immune cells and minimal proximal enhancers to improve vector safety. This lentiviral vector efficiently transduces major dendritic cell subsets in vivo. With a mycobacterial immunogen, we obs...

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Detalles Bibliográficos
Autores principales: Ku, Min Wen, Authié, Pierre, Nevo, Fabien, Souque, Philippe, Bourgine, Maryline, Romano, Marta, Charneau, Pierre, Majlessi, Laleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192903/
https://www.ncbi.nlm.nih.gov/pubmed/34112936
http://dx.doi.org/10.1038/s42003-021-02251-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192903/
https://www.ncbi.nlm.nih.gov/pubmed/34112936
http://dx.doi.org/10.1038/s42003-021-02251-6

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