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Lentiviral vector induces high-quality memory T cells via dendritic cells transduction
We report a lentiviral vector harboring the human β2-microglobulin promoter, with predominant expression in immune cells and minimal proximal enhancers to improve vector safety. This lentiviral vector efficiently transduces major dendritic cell subsets in vivo. With a mycobacterial immunogen, we obs...
Autores principales: | Ku, Min Wen, Authié, Pierre, Nevo, Fabien, Souque, Philippe, Bourgine, Maryline, Romano, Marta, Charneau, Pierre, Majlessi, Laleh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192903/ https://www.ncbi.nlm.nih.gov/pubmed/34112936 http://dx.doi.org/10.1038/s42003-021-02251-6 |
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