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Cell segmentation-free inference of cell types from in situ transcriptomics data

Multiplexed fluorescence in situ hybridization techniques have enabled cell-type identification, linking transcriptional heterogeneity with spatial heterogeneity of cells. However, inaccurate cell segmentation reduces the efficacy of cell-type identification and tissue characterization. Here, we pre...

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Detalles Bibliográficos
Autores principales: Park, Jeongbin, Choi, Wonyl, Tiesmeyer, Sebastian, Long, Brian, Borm, Lars E., Garren, Emma, Nguyen, Thuc Nghi, Tasic, Bosiljka, Codeluppi, Simone, Graf, Tobias, Schlesner, Matthias, Stegle, Oliver, Eils, Roland, Ishaque, Naveed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192952/
https://www.ncbi.nlm.nih.gov/pubmed/34112806
http://dx.doi.org/10.1038/s41467-021-23807-4