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Rational approach to drug discovery for human schistosomiasis

Human schistosomiasis is a debilitating, life-threatening disease affecting more than 229 million people in as many as 78 countries. There is only one drug of choice effective against all three major species of Schistosoma, praziquantel (PZQ). However, as with many monotherapies, evidence for resist...

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Detalles Bibliográficos
Autores principales: LoVerde, Philip T., Alwan, Sevan N., Taylor, Alexander B., Rhodes, Jayce, Chevalier, Frédéric D., Anderson, Timothy JC., McHardy, Stanton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193065/
https://www.ncbi.nlm.nih.gov/pubmed/34111649
http://dx.doi.org/10.1016/j.ijpddr.2021.05.002