Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers

The present study evaluates the crystal growth rate of amorphous drugs when dispersed in different ternary polymeric amorphous solid dispersions (ASDs) in the presence of surfactants. Specifically, ternary ASDs of aprepitant (APT, selected as a model drug) were prepared via melt-quench cooling by ev...

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Detalles Bibliográficos
Autores principales: Kapourani, Afroditi, Tzakri, Theodora, Valkanioti, Vasiliki, Kontogiannopoulos, Konstantinos N., Barmpalexis, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193146/
https://www.ncbi.nlm.nih.gov/pubmed/34151251
http://dx.doi.org/10.1016/j.ijpx.2021.100086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193146/
https://www.ncbi.nlm.nih.gov/pubmed/34151251
http://dx.doi.org/10.1016/j.ijpx.2021.100086

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