Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

A deep eutectic solvent (DES) is a eutectic system consisting of hydrogen bond donor and acceptor has been suggested as a promising formulation strategy for poorly soluble drugs. A DES consisting of choline chloride and levulinic acid in a 1:2  molar ratio was used to formulate a liquid solution of...

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Detalles Bibliográficos
Autores principales: Palmelund, Henrik, Eriksen, Jonas B., Bauer-Brandl, Annette, Rantanen, Jukka, Löbmann, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193149/
https://www.ncbi.nlm.nih.gov/pubmed/34151250
http://dx.doi.org/10.1016/j.ijpx.2021.100083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193149/
https://www.ncbi.nlm.nih.gov/pubmed/34151250
http://dx.doi.org/10.1016/j.ijpx.2021.100083

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