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Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism

Metabolic flux analysis (MFA) is widely used to estimate intracellular fluxes. Conventional MFA, however, is limited to continuous cultures and the mid-exponential growth phase of batch cultures. Dynamic MFA (DMFA) has emerged to characterize time-resolved metabolic fluxes for the entire culture per...

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Detalles Bibliográficos
Autores principales: Martínez, Verónica S., Buchsteiner, Maria, Gray, Peter, Nielsen, Lars K., Quek, Lake-Ee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193249/
https://www.ncbi.nlm.nih.gov/pubmed/34150508
http://dx.doi.org/10.1016/j.meteno.2015.06.001