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Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism
Metabolic flux analysis (MFA) is widely used to estimate intracellular fluxes. Conventional MFA, however, is limited to continuous cultures and the mid-exponential growth phase of batch cultures. Dynamic MFA (DMFA) has emerged to characterize time-resolved metabolic fluxes for the entire culture per...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193249/ https://www.ncbi.nlm.nih.gov/pubmed/34150508 http://dx.doi.org/10.1016/j.meteno.2015.06.001 |