Heterologous expression of MlcE in Saccharomyces cerevisiae provides resistance to natural and semi-synthetic statins

Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the key enzyme in cholesterol biosynthesis. Their extensive use in treatment and prevention of cardiovascular diseases placed statins among the best selling drugs. Construction of Saccharomyces cerevisiae cell factory for the...

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Detalles Bibliográficos
Autores principales: Ley, Ana, Coumou, Hilde Cornelijne, Frandsen, Rasmus John Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193252/
https://www.ncbi.nlm.nih.gov/pubmed/34150514
http://dx.doi.org/10.1016/j.meteno.2015.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193252/
https://www.ncbi.nlm.nih.gov/pubmed/34150514
http://dx.doi.org/10.1016/j.meteno.2015.09.003

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