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Downregulation of ACE2 expression by SARS-CoV-2 worsens the prognosis of KIRC and KIRP patients via metabolism and immunoregulation

Background: Angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) allow entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells and play essential roles in cancer therapy. However, the functions of ACE2 and TMPRSS2 in kidney cancer remain...

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Detalles Bibliográficos
Autores principales: Tang, Qian, Wang, Yue, Ou, Ling, Li, Jieling, Zheng, Kai, Zhan, Hui, Gu, Jiayu, Zhou, Guibao, Xie, Shouxia, Zhang, Jianping, Huang, Wei, Wang, Shaoxiang, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193256/
https://www.ncbi.nlm.nih.gov/pubmed/34131396
http://dx.doi.org/10.7150/ijbs.57802