Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells

Ovarian cancer is a common cause of death among gynecological cancers. Although ovarian cancer initially responds to chemotherapy, frequent recurrence in patients remains a therapeutic challenge. Pyruvate kinase M2 (PKM2) plays a pivotal role in regulating cancer cell survival. However, its therapeu...

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Detalles Bibliográficos
Autores principales: Park, Jae Hyeon, Kundu, Amit, Lee, Su Hyun, Jiang, ChunXue, Lee, Song Hee, Kim, Ye Seul, Kyung, So Young, Park, So Hyun, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193271/
https://www.ncbi.nlm.nih.gov/pubmed/34131394
http://dx.doi.org/10.7150/ijbs.59855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193271/
https://www.ncbi.nlm.nih.gov/pubmed/34131394
http://dx.doi.org/10.7150/ijbs.59855

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