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Logical modelling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions

Dendritic cells (DCs) are the major specialized antigen-presenting cells, thereby connecting innate and adaptive immunity. Because of their role in establishing adaptive immunity, they constitute promising targets for immunotherapy. Monocytes can differentiate into DCs in vitro in the presence of co...

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Detalles Bibliográficos
Autores principales: Nuñez-Reza, Karen J., Naldi, Aurélien, Sánchez-Jiménez, Arantza, Leon-Apodaca, Ana V., Santana, M. Angélica, Thomas-Chollier, Morgane, Thieffry, Denis, Medina-Rivera, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193469/
https://www.ncbi.nlm.nih.gov/pubmed/34123352
http://dx.doi.org/10.1098/rsfs.2020.0061