G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells

While technological advances in radiation oncology have led to a more precise delivery of radiation dose and a decreased risk of side effects, there is still a need to better understand the mechanisms underlying DNA damage response (DDR) at the DNA and cytogenetic levels, and to overcome tumor resis...

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Detalles Bibliográficos
Autores principales: Nikolakopoulou, Aggeliki, Soni, Aashish, Habibi, Martha, Karaiskos, Pantelis, Pantelias, Gabriel, Terzoudi, Georgia I., Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193504/
https://www.ncbi.nlm.nih.gov/pubmed/34123995
http://dx.doi.org/10.3389/fpubh.2021.675095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193504/
https://www.ncbi.nlm.nih.gov/pubmed/34123995
http://dx.doi.org/10.3389/fpubh.2021.675095

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