Cargando…
G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells
While technological advances in radiation oncology have led to a more precise delivery of radiation dose and a decreased risk of side effects, there is still a need to better understand the mechanisms underlying DNA damage response (DDR) at the DNA and cytogenetic levels, and to overcome tumor resis...
Autores principales: | Nikolakopoulou, Aggeliki, Soni, Aashish, Habibi, Martha, Karaiskos, Pantelis, Pantelias, Gabriel, Terzoudi, Georgia I., Iliakis, George |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193504/ https://www.ncbi.nlm.nih.gov/pubmed/34123995 http://dx.doi.org/10.3389/fpubh.2021.675095 |
Ejemplares similares
-
Comparison and Evaluation of Different Radiotherapy Techniques Using Biodosimetry Based on Cytogenetics
por: Nikolakopoulou, Aggeliki, et al.
Publicado: (2021) -
DNA Double-Strand Break Repair as Determinant of Cellular Radiosensitivity to Killing and Target in Radiation Therapy
por: Mladenov, Emil, et al.
Publicado: (2013) -
CRISPR/Cas9 ribonucleoprotein-mediated knockin generation in hTERT-RPE1 cells
por: Ghetti, Sabrina, et al.
Publicado: (2021) -
Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes
por: Hindul, Naushin L., et al.
Publicado: (2022) -
The Use of Genotoxicity Endpoints as Biomarkers of Low Dose Radiation Exposure in Interventional Cardiology
por: Habibi, Martha, et al.
Publicado: (2021)