High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma

Head and neck paragangliomas (HNPGLs) are rare neoplasms that represent difficult treatment paradigms in neurotology. Germline mutations in genes encoding succinate dehydrogenase (SDH) are the cause of nearly all familial HNPGLs. However, the molecular mechanisms underlying tumorigenesis remain uncl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhigang, Chen, Hongsai, Xue, Lu, He, Weiwei, Shu, Wenying, Wu, Hao, Wang, Zhaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193622/
https://www.ncbi.nlm.nih.gov/pubmed/34118692
http://dx.doi.org/10.1016/j.tranon.2021.101146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193622/
https://www.ncbi.nlm.nih.gov/pubmed/34118692
http://dx.doi.org/10.1016/j.tranon.2021.101146

Ejemplares similares