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Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes

Immune checkpoint inhibitor (ICI) immunotherapies have vastly improved therapeutic outcomes for patients with certain cancer types, but these responses only manifest in a small percentage of all cancer patients. The goal of the present study was to improve checkpoint therapy efficacy by utilizing an...

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Detalles Bibliográficos
Autores principales: Lou, Jiaying, Dong, Jialin, Xu, Ruijun, Zeng, Hui, Fang, Lijuan, Wu, Yi, Liu, Yang, Wang, Shibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193643/
https://www.ncbi.nlm.nih.gov/pubmed/34060602
http://dx.doi.org/10.1042/BSR20204186