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Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice

AIMS: Naltrexone is a mu opioid receptor (MOR) antagonist used to treat drug dependence in patients. Previous reports indicated that MOR antagonists reduced neurodegeneration and inflammation after brain injury. The purpose of this study was to evaluate the neuroprotective effect of naltrexone in ce...

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Detalles Bibliográficos
Autores principales: Wang, Yu‐Syuan, Hung, Tsai‐Wei, Bae, Eun‐Kyung, Wu, Kuo‐Jen, Hsieh, Wei, Yu, Seong‐Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193702/
https://www.ncbi.nlm.nih.gov/pubmed/34018697
http://dx.doi.org/10.1111/cns.13655