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AI-guided discovery of the invariant host response to viral pandemics

BACKGROUND: Coronavirus Disease 2019 (Covid-19) continues to challenge the limits of our knowledge and our healthcare system. Here we sought to define the host immune response, a.k.a, the “cytokine storm” that has been implicated in fatal COVID-19 using an AI-based approach. METHOD: Over 45,000 tran...

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Detalles Bibliográficos
Autores principales: Sahoo, Debashis, Katkar, Gajanan D., Khandelwal, Soni, Behroozikhah, Mahdi, Claire, Amanraj, Castillo, Vanessa, Tindle, Courtney, Fuller, MacKenzie, Taheri, Sahar, Rogers, Thomas F., Beutler, Nathan, Ramirez, Sydney I., Rawlings, Stephen A., Pretorius, Victor, Smith, Davey M., Burton, Dennis R., Alexander, Laura E. Crotty, Duran, Jason, Crotty, Shane, Dan, Jennifer M., Das, Soumita, Ghosh, Pradipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193764/
https://www.ncbi.nlm.nih.gov/pubmed/34127431
http://dx.doi.org/10.1016/j.ebiom.2021.103390