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Protein Arginine Methyltransferase 5 Promotes Esophageal Squamous Cell Carcinoma Proliferation and Metastasis via LKB1/AMPK/mTOR Signaling Pathway

Background: Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer in the world. Protein arginine methyltransferase 5 (PRMT5), an enzyme that catalyzes symmetric and asymmetric methylation on arginine residues of histone and non-histone proteins, is overexpressed in many cancers....

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Detalles Bibliográficos
Autores principales: Chen, Yu-ru, Li, Hua-ni, Zhang, Lian-jun, Zhang, Chong, He, Jin-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193860/
https://www.ncbi.nlm.nih.gov/pubmed/34124017
http://dx.doi.org/10.3389/fbioe.2021.645375