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UMIc: A Preprocessing Method for UMI Deduplication and Reads Correction

A recent refinement in high-throughput sequencing involves the incorporation of unique molecular identifiers (UMIs), which are random oligonucleotide barcodes, on the library preparation steps. A UMI adds a unique identity to different DNA/RNA input molecules through polymerase chain reaction (PCR)...

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Detalles Bibliográficos
Autores principales: Tsagiopoulou, Maria, Maniou, Maria Christina, Pechlivanis, Nikolaos, Togkousidis, Anastasis, Kotrová, Michaela, Hutzenlaub, Tobias, Kappas, Ilias, Chatzidimitriou, Anastasia, Psomopoulos, Fotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193862/
https://www.ncbi.nlm.nih.gov/pubmed/34122513
http://dx.doi.org/10.3389/fgene.2021.660366