Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20

BACKGROUND: Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) underlines much of the pathology of Parkinson’s disease (PD), but the existence of an endogenous neurogenic system that could be targeted as a therapeutic strategy has been controversial. BNN-20 is a synthetic, BDN...

Descripción completa

Detalles Bibliográficos
Autores principales: Mourtzi, Theodora, Dimitrakopoulos, Dimitrios, Kakogiannis, Dimitrios, Salodimitris, Charalampos, Botsakis, Konstantinos, Meri, Danai Kassandra, Anesti, Maria, Dimopoulou, Aggeliki, Charalampopoulos, Ioannis, Gravanis, Achilleas, Matsokis, Nikolaos, Angelatou, Fevronia, Kazanis, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193896/
https://www.ncbi.nlm.nih.gov/pubmed/34112234
http://dx.doi.org/10.1186/s13287-021-02398-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193896/
https://www.ncbi.nlm.nih.gov/pubmed/34112234
http://dx.doi.org/10.1186/s13287-021-02398-3

Ejemplares similares