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Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20
BACKGROUND: Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) underlines much of the pathology of Parkinson’s disease (PD), but the existence of an endogenous neurogenic system that could be targeted as a therapeutic strategy has been controversial. BNN-20 is a synthetic, BDN...
Autores principales: | Mourtzi, Theodora, Dimitrakopoulos, Dimitrios, Kakogiannis, Dimitrios, Salodimitris, Charalampos, Botsakis, Konstantinos, Meri, Danai Kassandra, Anesti, Maria, Dimopoulou, Aggeliki, Charalampopoulos, Ioannis, Gravanis, Achilleas, Matsokis, Nikolaos, Angelatou, Fevronia, Kazanis, Ilias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193896/ https://www.ncbi.nlm.nih.gov/pubmed/34112234 http://dx.doi.org/10.1186/s13287-021-02398-3 |
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