Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

BACKGROUND: Genetically susceptible individuals can develop malignancies after irradiation of normal tissues. In the context of therapeutic irradiation, it is not known whether irradiating benign neoplasms in susceptible individuals promotes neoplastic transformation and worse clinical outcomes. Ind...

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Detalles Bibliográficos
Autores principales: Laurent, Danny, Smith, Abbi E, Bessler, Waylan K, Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E, Clapp, D Wade, Nakamura, Jean L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193912/
https://www.ncbi.nlm.nih.gov/pubmed/34131650
http://dx.doi.org/10.1093/noajnl/vdab063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193912/
https://www.ncbi.nlm.nih.gov/pubmed/34131650
http://dx.doi.org/10.1093/noajnl/vdab063

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