Cargando…

TPX2 Enhanced the Activation of the HGF/ETS-1 Pathway and Increased the Invasion of Endocrine-Independent Prostate Carcinoma Cells

The prognosis for endocrine-independent prostate carcinoma is still poor due to its highly metastatic feature. In the present work, TPX2 (the targeting protein for Xklp2), which is known as a micro-tubulin interacted protein, was identified as a novel coactivator of ETS-1, a transcription factor tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Hongqing, Liu, Mingsheng, Shao, Tao, Xie, Pingbo, Zhu, Shaojie, Wang, Wei, Miao, Qiong, Peng, Jiaxi, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193931/
https://www.ncbi.nlm.nih.gov/pubmed/34123781
http://dx.doi.org/10.3389/fonc.2021.618540