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Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic pain disorders and migraine. Antidepressants are associated with both therapeutic and untoward effects, and their use in the elderly has tripled...

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Detalles Bibliográficos
Autores principales: Bang, Eunyoung, Tobery, Angelika, Montgomery, Karienn S., Fincher, Annette S., Earnest, David J., Murchison, David A., Griffith, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193944/
https://www.ncbi.nlm.nih.gov/pubmed/34122049
http://dx.doi.org/10.3389/fnagi.2021.673155