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Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging
The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic pain disorders and migraine. Antidepressants are associated with both therapeutic and untoward effects, and their use in the elderly has tripled...
Autores principales: | Bang, Eunyoung, Tobery, Angelika, Montgomery, Karienn S., Fincher, Annette S., Earnest, David J., Murchison, David A., Griffith, William H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193944/ https://www.ncbi.nlm.nih.gov/pubmed/34122049 http://dx.doi.org/10.3389/fnagi.2021.673155 |
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