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Tyrosine Kinase ROR1 as a Target for Anti-Cancer Therapies

Receptor tyrosine kinase ROR1 plays an essential role in embryogenesis and is overexpressed in many types of malignant tumors. Studies have demonstrated that it plays an important role in oncogenesis by activating cell survival signaling events, particularly the non-canonical WNT signaling pathway....

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Detalles Bibliográficos
Autores principales: Zhao, Yuming, Zhang, Dengyang, Guo, Yao, Lu, Bo, Zhao, Zhizhuang Joe, Xu, Xiaojun, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193947/
https://www.ncbi.nlm.nih.gov/pubmed/34123850
http://dx.doi.org/10.3389/fonc.2021.680834