STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease

BACKGROUND: The aetiology of inflammatory bowel disease (IBD) is related to genetics and epigenetics. Epigenetic regulation of the pathogenesis of IBD has not been well defined. Here, we investigated the role of H3K27ac events in the pathogenesis of IBD. Based on previous ChIP-seq and RNA-seq assays...

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Detalles Bibliográficos
Autores principales: Yu, Ya-Li, Chen, Meng, Zhu, Hua, Zhuo, Ming-Xing, Chen, Ping, Mao, Yu-Juan, Li, Lian-Yun, Zhao, Qiu, Wu, Min, Ye, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194145/
https://www.ncbi.nlm.nih.gov/pubmed/34112215
http://dx.doi.org/10.1186/s13148-021-01101-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194145/
https://www.ncbi.nlm.nih.gov/pubmed/34112215
http://dx.doi.org/10.1186/s13148-021-01101-w

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