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H3.3 kinetics predicts chromatin compaction status of parental genomes in early embryos

BACKGROUND: After fertilization, the fusion of gametes results in the formation of totipotent zygote. During sperm-egg fusion, maternal factors participate in parental chromatin remodeling. H3.3 is a histone H3 variant that plays essential roles in mouse embryogenesis. METHODS: Here, we used transge...

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Detalles Bibliográficos
Autores principales: Guo, Shi-meng, Liu, Xing-ping, Zhou, Li-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194155/
https://www.ncbi.nlm.nih.gov/pubmed/34116678
http://dx.doi.org/10.1186/s12958-021-00776-3