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Therapeutic potential of targeting Tfr/Tfh cell balance by low-dose-IL-2 in active SLE: a post hoc analysis from a double-blind RCT study

OBJECTIVE: To investigate the regulation of T follicular regulatory (Tfr) and T follicular (Tfh) cell subtypes by low-dose IL-2 in systemic lupus erythematosus (SLE) in a randomized, double-blind, placebo-controlled clinical trial. METHODS: A post hoc analysis was performed in a randomized cohort of...

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Detalles Bibliográficos
Autores principales: Miao, Miao, Xiao, Xian, Tian, Jiayi, Zhufeng, Yunzhi, Feng, Ruiling, Zhang, Ruijun, Chen, Jiali, Zhang, Xiaoying, Huang, Bo, Jin, Yuebo, Sun, Xiaolin, He, Jing, Li, Zhanguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194162/
https://www.ncbi.nlm.nih.gov/pubmed/34116715
http://dx.doi.org/10.1186/s13075-021-02535-6